Familial congenital complete heart block and maternal systemic lupus erythematosis.

Familial congenital complete heart block and maternal systemic lupus erythematosis.

A family is reported in which two siblings had congenital complete heart block with resultant congestive heart failure, the father and paternal grandfather show adult-onset conduction defects, and the mother has systemic lupus erythematosis. The interaction of heredity and environment is discussed in this context. A review of the literature on familial complete heart block suggests that so-call...

CASE REPORTS Familial Congenital Complete Heart Block and Maternal Systemic Lupus Erythematosis

FAMILIAL COMPLETE HEART BLOCK (CHB) has been described by a number of observers since the report by Morquio' in 1901. Among those reported are thirteen families with multiple cases of well-documented congenital CHB2-14 using the classic criteria of Yater'5 and eliminating those with intracardiac defects. More recently, an association has been noted between congenital CHB and maternal connective...

Congenital complete heart block and persistent ductus arteriosus associated with maternal systemic lupus erythematosus.

Congenital complete heart block can occur in sibs with and without associated congenital heart defects.' This has been associated with different histological changes, but the ultimate cause has remained obscure. Recently there have been reports of an association between congenital heart block and maternal systemic lupus erythematosus.24 This report concerns two sisters with congenital complete ...

Congenital complete heart block.

Congenital Complete Heart Block.

Few of the reported cases of congenital complete heart block have been over twenty years of age. It seems, therefore, worth reporting seven cases who are in good health at various ages between 22 and 42 years. This aetiological factor should, therefore, be thought of in middle-aged and even in elderly patients with complete heart block of unknown oetiology. Campbell and Suzman (1934), reporting...